Determination of Myocardial FFA Elimination Rates by Functional Images of Uncorrected Half-Time Values

F. C. Visser; A. Van Lingen; G. Westera; M. J. Eenige van; W. Den Hollander; E. E. Van der Wall; G. A. K. Heidendal; J. P. Roos

doi:10.1055/s-0038-1624257

Nuklearmedizin - NuclearMedicine, Table of Contents

Nuklearmedizin 1984; 23(06): 277-282
DOI: 10.1055/s-0038-1624257

Originalarbeiten — Original Articles

Schattauer GmbH

Determination of Myocardial FFA Elimination Rates by Functional Images of Uncorrected Half-Time Values

Bestimmung von FFA-EIiminationsraten des Myokards anhand von Funktionsbildem unkorrigierter Halb wertszeiten

F. C. Visser

^*From the Dept, of Cardiology, Amsterdam, The Netherlands

,

A. Van Lingen

^**Dept, of Nuclear Medicine, Free University Hospital, Amsterdam, The Netherlands

,

G. Westera

^**Dept, of Nuclear Medicine, Free University Hospital, Amsterdam, The Netherlands

,

M. J. Eenige van

^*From the Dept, of Cardiology, Amsterdam, The Netherlands

,

W. Den Hollander

^**Dept, of Nuclear Medicine, Free University Hospital, Amsterdam, The Netherlands

,

E. E. Van der Wall

^*From the Dept, of Cardiology, Amsterdam, The Netherlands

,

G. A. K. Heidendal

^**Dept, of Nuclear Medicine, Free University Hospital, Amsterdam, The Netherlands

,

J. P. Roos

^*From the Dept, of Cardiology, Amsterdam, The Netherlands

› Author Affiliations

Abstract

Summary

This paper presents an alternative method of demarcating regions of in terest over the myocardium after ad ministration of ¹²³I-heptadecanoic acid to patients with coronary artery disea se. In a matrix of 32 × 32 pixels the elimination rates of the radioactivity, which are not corrected for back ground activity, are visualized per pixel in a functional image. The func tional image showed areas in the myocardium with high values of uncorrected elimination rates. These areas corresponded with the tracer defects on the scintigram. Corrected elimination rates obtained from re gions of interest of functional images were comparable with those of scinti grams. Thus based on functional im ages of uncorrected elimination rates a reliable, objective determination of regions of interest over normal and abnormal myocardium can be made.

Zusammenfassung

Beschrieben wird eine al ternative Methode für die Abgren zung von Regions of Interest (ROI) über dem Myokard nach Applikation von ¹²³J-Heptadekansäure bei Patien ten mit koronarer Herzerkrankung. In einer Matrix von 32 × 32 Pixel werden die Eliminationsraten der Aktivität pro Pixel, nicht korrigiert für die Hintergrundaktivität, als Funktions bild gezeigt. Dieses zeigt Gebiete des Myokards mit hohen Werten für die unkorrigierten Eliminationsraten. Diese Bezirke stimmen mit Speicher defekten im Szintigramm überein. Die korrigierten Eliminationsraten, wel che aus Regions of Interest von Funk tionsbildern erhalten werden, waren mit denen des Szintigramms vergleich bar. Folglich kann eine zuverlässige und objektive Abgrenzung von Regions of Interest über normalem und abnormalem Myokard anhand von Funktionsbildern und korrigierten Eli minationsraten vorgenommen wer den.

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References

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